anti-WT1 (human), Rabbit Monoclonal (RM516)

Product description: WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma and desmoplastic small round cell tumor. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.

Alternate Names/Synonyms: Wilms Tumor Protein; WT33

Product Type: Recombinant Antibody

Clone: RM516

Isotype: Rabbit IgG

Immunogen: A peptide corresponding to residues near the N-terminus of human WT1.

Applications: IHC, WB

Species Crossreactivity: Human

Specificity: This antibody reacts to human WT1 (Wilms tumor protein).

Long Term Storage: -20°C

Shipping: BLUE ICE

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

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