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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Apigenin is an antioxidant plant flavonoid with anti-inflammatory, angiogenic, neuroprotective and anticancer properties. It may induce apoptosis and inhibit proliferation of tumor cells by arresting the cell cycle at the G2/M phase. Inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression. Also known to be a MAP kinase inhibitor and a selectively inhibitor of casein kinase 2 (CK2). It is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression. Shown to selectively inhibits chymotrypsin-like and trypsin-like proteasome catalytic activity.
Alternate Names/Synonyms: Chamomile; Flavone; NSC 83244; Versulin; 4',5,7-Trihydroxyflavone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
CAS: 520-36-5
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