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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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GFRAL (mouse):Fc (mouse) (rec.)
100 µg
photos non contractuelles
Détails Produit
Product Description: GFRAL (GDNF receptor alpha-like) is a distant member of the GDNFR family of proteins. Mouse GFR alpha-like contains a 330aa extracellular domain. It is expressed on hindbrain neurons of the CNS and functions as an anti-apoptotic molecule during neuronal stress. GFRAL is a functional receptor for GDF15, facilitating weight-loss functions of the protein through c-Ret downstream signaling. GFRAL and GDF15 signaling is implicated in diet-based obesity and insulin resistance.
Alternate Names/Synonyms: GDNF Family Receptor alpha-like; Gral; Glial Cellline-derived Neurotrophic Factor Receptor alpha-like; GFR alpha-like
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