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10 µg

Ref. CHI-HF-210SCF-C010
Chimerigen

photos non contractuelles

Neuf 170.00 H.T.

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Détails Produit

Product Description: Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF) and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.

Alternate Names/Synonyms: Stem Cell Factor; c-Kit Ligand; Kit Ligand; Mast Cell Grow Factor; MGF

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