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The Source for Rare Active Natural Products

 
Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
 
 
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.

 

Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
 
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.
TargoSets™ - Screening Sets of characterized Natural Products
 
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
 
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
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Phomoxanthone A Phomoxanthone A 5 mg Ref. BVT-0453-M005 Marque BioViotica 360.00 € H.T.
 
Venturicidin A Venturicidin A 1 mg Ref. BVT-0454-M001 Marque BioViotica 135.00 € H.T.
 
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Pyridomycin Pyridomycin 1 mg Ref. BVT-0455-M001 Marque BioViotica 305.00 € H.T.
 
Telithromycin Telithromycin 1 mg Ref. BVT-0456-M001 Marque BioViotica 45.00 € H.T.
 
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Telithromycin Telithromycin 10 mg Ref. BVT-0456-M010 Marque BioViotica 160.00 € H.T.
 
Luteoreticulin Luteoreticulin 500 µg Ref. BVT-0457-C500 Marque BioViotica 160.00 € H.T.
 
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Luteoreticulin Luteoreticulin 1 mg Ref. BVT-0457-M001 Marque BioViotica 285.00 € H.T.
 
Cochliodone A Cochliodone A 1 mg Ref. BVT-0458-M001 Marque BioViotica 170.00 € H.T.
 
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Chaetoglobosin C Chaetoglobosin C 1 mg Ref. BVT-0460-M001 Marque BioViotica 245.00 € H.T.
 
Chaetoglobosin F Chaetoglobosin F 1 mg Ref. BVT-0461-M001 Marque BioViotica 205.00 € H.T.
 
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Lysolipin I Lysolipin I 5 mg Ref. BVT-0037-M005 Marque BioViotica 575.00 € H.T.
 
17-AAG 17-AAG 5 mg Ref. BVT-0244-M005 Marque BioViotica 80.00 € H.T.
 
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Alternariol monomethyl ether Alternariol monomethyl ether 5 mg Ref. BVT-0323-M005 Marque BioViotica 505.00 € H.T.
 
Alternariol monomethyl ether Alternariol monomethyl ether 10 mg Ref. BVT-0323-M010 Marque BIOVIOTICA 630.00 € H.T.
 
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Culpin Culpin 1 mg Ref. BVT-0462-M001 Marque BioViotica 105.00 € H.T.
 
Culpin Culpin 5 mg Ref. BVT-0462-M005 Marque BioViotica 320.00 € H.T.
 
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Culpin Culpin 10 mg Ref. BVT-0462-M010 Marque BioViotica 500.00 € H.T.
 
Lupallene B Lupallene B 1 mg Ref. BVT-0466-M001 Marque BioViotica 130.00 € H.T.
 
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Lupallene B Lupallene B 5 mg Ref. BVT-0466-M005 Marque BioViotica 390.00 € H.T.
 
Lupallene D Lupallene D 1 mg Ref. BVT-0467-M001 Marque BioViotica 130.00 € H.T.
 
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Lupallene D Lupallene D 5 mg Ref. BVT-0467-M005 Marque BioViotica 390.00 € H.T.
 
Dimethylsulfoniopropionate (DMSP) . hydrochloride Dimethylsulfoniopropionate (DMSP) . hydrochloride 100 mg Ref. BVT-0468-M100 Marque BioViotica 135.00 € H.T.
 
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Fridamycin A Fridamycin A 1 mg Ref. BVT-0469-M001 Marque BioViotica 100.00 € H.T.
 
Fridamycin B Fridamycin B 1 mg Ref. BVT-0470-M001 Marque BioViotica 100.00 € H.T.
 
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Fridamycin E Fridamycin E 1 mg Ref. BVT-0472-M001 Marque BioViotica 100.00 € H.T.
 
Violacein Violacein 1 mg Ref. BVT-0473-M001 Marque BioViotica 435.00 € H.T.
 
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(+)-Rubiginone B2 (+)-Rubiginone B2 1mg Ref. BVT-0026-M01 Marque BIOVIOTICA 125.00 € H.T.
 
Alternariol Alternariol 1 mg Ref. BVT-0465-M001 Marque BioViotica 90.00 € H.T.
 
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Alternariol Alternariol 5 mg Ref. BVT-0465-M005 Marque BioViotica 295.00 € H.T.
 
Rubiginone B2 Rubiginone B2 1 mg Ref. BVT-0026-M001 Marque BioViotica 155.00 € H.T.
 
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Terreic acid Terreic acid 1 mg Ref. BVT-0477-M001 Marque BioViotica 65.00 € H.T.
 
Terreic acid Terreic acid 5 mg Ref. BVT-0477-M005 Marque BioViotica 205.00 € H.T.
 
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Helvolic acid Helvolic acid 5 mg Ref. BVT-0435-M005 Marque BioViotica 235.00 € H.T.
 
Decoyinine Decoyinine 5 mg Ref. BVT-0030-M005 Marque BioViotica 315.00 € H.T.
 
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Concanamycin A (high purity) Concanamycin A (high purity) 5 mg Ref. BVT-0237-M005 Marque BioViotica 1400.00 € H.T.
 
Concanamycin B (high purity) Concanamycin B (high purity) 1 mg Ref. BVT-0253-M001 Marque BioViotica 760.00 € H.T.
 
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Concanamycin C (high purity) Concanamycin C (high purity) 1 mg Ref. BVT-0254-M001 Marque BioViotica 770.00 € H.T.
 
Collinolactone Collinolactone 250 µg Ref. BVT-0480-C250 Marque BioViotica 170.00 € H.T.
 
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Collinolactone Collinolactone 1 mg Ref. BVT-0480-M001 Marque BioViotica 515.00 € H.T.
 
Rubiginone A2 Rubiginone A2 5 mg Ref. BVT-0023-M005 Marque BioViotica 630.00 € H.T.
 
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Rubiginone D2 Rubiginone D2 5 mg Ref. BVT-0024-M005 Marque BioViotica 630.00 € H.T.
 
Palmarumycin C3-5,8-quinone Palmarumycin C3-5,8-quinone 5 mg Ref. BVT-0066-M005 Marque BioViotica 505.00 € H.T.
 
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Mutolide Mutolide 5 mg Ref. BVT-0070-M005 Marque BioViotica 505.00 € H.T.
 
Isatropolone A Isatropolone A 5 mg Ref. BVT-0080-M005 Marque BioViotica 405.00 € H.T.
 
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Pyrrolcarbonyltaloside Pyrrolcarbonyltaloside 5 mg Ref. BVT-0095-M005 Marque BioViotica 315.00 € H.T.
 
Curvulin Curvulin 5 mg Ref. BVT-0097-M005 Marque BioViotica 475.00 € H.T.
 
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MM 47755 MM 47755 5 mg Ref. BVT-0282-M005 Marque BioViotica 540.00 € H.T.
 
Psicofuranine Psicofuranine 5 mg Ref. BVT-0284-M005 Marque BioViotica 380.00 € H.T.
 
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Agistatin D Agistatin D 5 mg Ref. BVT-0286-M005 Marque BioViotica 435.00 € H.T.
 
Diastovaricin I Diastovaricin I 5 mg Ref. BVT-0381-M005 Marque BioViotica 505.00 € H.T.
 
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