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AVANTI POLAR LIPIDS , CYGNUS , LARODAN , ADIPOGEN , MYBIOSOURCE , SERVA NORDMARK, BIOWORLD, EDGEBIO , PANREAC APPLICHEM
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Product description: Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal, lysosomal and vacuolar acidification. Prevents lysosomal Ca2+ uptake. Inhibitor of autophagic degradation by rising pH and thus inactivating the lysosomal acid hydrolases. Neuroprotective.
Alternate Names/Synonyms: NSC381866
Product Type: Chemical
Molecular Formula: C35H58O9
Molecular Weight: 622.8
CAS: 88899-55-2
Source / Host: Isolated from Streptomyces griseus.
Purity: >98% (HPLC)
InChiKey: XDHNQDDQEHDUTM-AZJYDCQCSA-N
Appearance White to off-white powder.
Solubility: Soluble in DMSO, 100% ethanol or methanol.
Short Term Storage: +4°C
Long Term Storage: -20°C
Shipping: AMBIENT
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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