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The Source for Rare Active Natural Products

Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.


Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.

TargoSets™ - Screening Sets of characterized Natural Products
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
Kendomycin Kendomycin 100 µg Ref. BVT-0001-C100 Marque BioViotica 75.00 H.T.
Seriniquinone Seriniquinone 5 mg Ref. BVT-0478-M005 Marque BioViotica 195.00 H.T.
Seriniquinone Seriniquinone 1 mg Ref. BVT-0478-M001 Marque BioViotica 65.00 H.T.
Seriniquinone Seriniquinone 10 mg Ref. BVT-0478-M010 Marque BioViotica 340.00 H.T.
Kendomycin Kendomycin 500 µg Ref. BVT-0001-C500 Marque BioViotica 150.00 H.T.
Pseurotin A Pseurotin A 1 mg Ref. BVT-0003-M001 Marque BioViotica 95.00 H.T.
Pseurotin A Pseurotin A 5 mg Ref. BVT-0003-M005 Marque BioViotica 310.00 H.T.
Bafilomycin B1 Bafilomycin B1 100 µg Ref. BVT-0004-C100 Marque BioViotica 55.00 H.T.
Bafilomycin B1 Bafilomycin B1 1 mg Ref. BVT-0004-M001 Marque BioViotica 95.00 H.T.
Chartreusin Chartreusin 5 mg Ref. BVT-0005-M005 Marque BioViotica 140.00 H.T.
Echinosporin Echinosporin 1 mg Ref. BVT-0006-M001 Marque BioViotica 140.00 H.T.
Echinosporin Echinosporin 5 mg Ref. BVT-0006-M005 Marque BioViotica 490.00 H.T.
gamma-Rubromycin gamma-Rubromycin 1 mg Ref. BVT-0007-M001 Marque BioViotica 85.00 H.T.
gamma-Rubromycin gamma-Rubromycin 5 mg Ref. BVT-0007-M005 Marque BioViotica 340.00 H.T.
Reticulol Reticulol 250 µg Ref. BVT-0011-C250 Marque BioViotica 80.00 H.T.
Reticulol Reticulol 1 mg Ref. BVT-0011-M001 Marque BioViotica 170.00 H.T.
Antibiotic UK-1 Antibiotic UK-1 250 µg Ref. BVT-0013-C250 Marque BioViotica 85.00 H.T.
Antibiotic UK-1 Antibiotic UK-1 1 mg Ref. BVT-0013-M001 Marque BioViotica 255.00 H.T.
Kojic acid Kojic acid 10 mg Ref. BVT-0019-M010 Marque BioViotica 50.00 H.T.
Rubiginone A2 Rubiginone A2 1 mg Ref. BVT-0023-M001 Marque BioViotica 150.00 H.T.
Rubiginone D2 Rubiginone D2 1 mg Ref. BVT-0024-M001 Marque BioViotica 150.00 H.T.
Mensacarcin Mensacarcin 1 mg Ref. BVT-0028-M001 Marque BioViotica 140.00 H.T.
Mensacarcin Mensacarcin 5 mg Ref. BVT-0028-M005 Marque BioViotica 415.00 H.T.
Aspyrone Aspyrone 1 mg Ref. BVT-0029-M001 Marque BioViotica 85.00 H.T.
Aspyrone Aspyrone 5 mg Ref. BVT-0029-M005 Marque BioViotica 290.00 H.T.
Decoyinine Decoyinine 1 mg Ref. BVT-0030-M001 Marque BioViotica 75.00 H.T.
Oxyplicacetin Oxyplicacetin 1 mg Ref. BVT-0031-M001 Marque BioViotica 120.00 H.T.
Polyketomycin Polyketomycin 1 mg Ref. BVT-0033-M001 Marque BioViotica 150.00 H.T.
Aspinonene Aspinonene 1 mg Ref. BVT-0035-M001 Marque BioViotica 85.00 H.T.
Aspinonene Aspinonene 5 mg Ref. BVT-0035-M005 Marque Bioviotica 340.00 H.T.
Resistomycin Resistomycin 1 mg Ref. BVT-0036-M001 Marque BioViotica 100.00 H.T.
Lysolipin I Lysolipin I 500 µg Ref. BVT-0037-C500 Marque BioViotica 105.00 H.T.
Lysolipin I Lysolipin I 1 mg Ref. BVT-0037-M001 Marque BioViotica 180.00 H.T.
CJ-21058 CJ-21058 1 mg Ref. BVT-0064-M001 Marque BioViotica 130.00 H.T.
CJ-21058 CJ-21058 5 mg Ref. BVT-0064-M005 Marque BioViotica 415.00 H.T.
Cladospirone bisepoxide Cladospirone bisepoxide 1 mg Ref. BVT-0065-M001 Marque BioViotica 140.00 H.T.
Palmarumycin C3-5,8-quinone Palmarumycin C3-5,8-quinone 1 mg Ref. BVT-0066-M001 Marque BioViotica 140.00 H.T.
Hypothemycin Hypothemycin 250 µg Ref. BVT-0067-C250 Marque BioViotica 120.00 H.T.
Hypothemycin Hypothemycin 1 mg Ref. BVT-0067-M001 Marque BioViotica 355.00 H.T.
Bafilomycin C1 Bafilomycin C1 1 mg Ref. BVT-0068-M001 Marque BioViotica 160.00 H.T.
Mutolide Mutolide 1 mg Ref. BVT-0070-M001 Marque BioViotica 140.00 H.T.
Palmarumycin C3 Palmarumycin C3 1 mg Ref. BVT-0078-M001 Marque BioViotica 140.00 H.T.
Palmarumycin C3 Palmarumycin C3 5 mg Ref. BVT-0078-M005 Marque BioViotica 415.00 H.T.
Benadrostin Benadrostin 500 µg Ref. BVT-0079-C500 Marque BioViotica 80.00 H.T.
Benadrostin Benadrostin 1 mg Ref. BVT-0079-M001 Marque BioViotica 130.00 H.T.
Isatropolone A Isatropolone A 1 mg Ref. BVT-0080-M001 Marque BioViotica 130.00 H.T.
Actinomycin D Actinomycin D 5 mg Ref. BVT-0089-M005 Marque BioViotica 55.00 H.T.
Actinomycin D Actinomycin D 25 mg Ref. BVT-0089-M025 Marque BioViotica 160.00 H.T.
Fumigaclavine A Fumigaclavine A 1 mg Ref. BVT-0090-M001 Marque BioViotica 150.00 H.T.
Fumigaclavine A Fumigaclavine A 5 mg Ref. BVT-0090-M005 Marque BioViotica 450.00 H.T.