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The Source for Rare Active Natural Products

 
Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
 
 
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.

 

Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
 
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.

TargoSets™ - Screening Sets of characterized Natural Products
 
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
 
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
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Kendomycin Kendomycin 100 µg Ref. BVT-0001-C100 Marque BIOVIOTICA 65.00 H.T.
 
Kendomycin Kendomycin 500 µg Ref. BVT-0001-C500 Marque BIOVIOTICA 135.00 H.T.
 
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Kendomycin Kendomycin 2.5 mg Ref. BVT-0001-MM25 Marque BIOVIOTICA 390.00 H.T.
 
Pseurotin A Pseurotin A 1 mg Ref. BVT-0003-M001 Marque BIOVIOTICA 85.00 H.T.
 
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Pseurotin A Pseurotin A 5 mg Ref. BVT-0003-M005 Marque BIOVIOTICA 255.00 H.T.
 
Bafilomycin B1 Bafilomycin B1 100 µg Ref. BVT-0004-C100 Marque BIOVIOTICA 45.00 H.T.
 
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Bafilomycin B1 Bafilomycin B1 1 mg Ref. BVT-0004-M001 Marque BIOVIOTICA 90.00 H.T.
 
Bafilomycin B1 Bafilomycin B1 5 mg Ref. BVT-0004-M005 Marque BIOVIOTICA 320.00 H.T.
 
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Chartreusin Chartreusin 5 mg Ref. BVT-0005-M005 Marque BIOVIOTICA 100.00 H.T.
 
Chartreusin Chartreusin 25 mg Ref. BVT-0005-M025 Marque BIOVIOTICA 400.00 H.T.
 
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Echinosporin Echinosporin 1 mg Ref. BVT-0006-M001 Marque BIOVIOTICA 120.00 H.T.
 
Echinosporin Echinosporin 5 mg Ref. BVT-0006-M005 Marque BIOVIOTICA 360.00 H.T.
 
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gamma-Rubromycin gamma-Rubromycin 1 mg Ref. BVT-0007-M001 Marque BIOVIOTICA 75.00 H.T.
 
gamma-Rubromycin gamma-Rubromycin 5 mg Ref. BVT-0007-M005 Marque BIOVIOTICA 300.00 H.T.
 
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Reticulol Reticulol 250 µg Ref. BVT-0011-C250 Marque BIOVIOTICA 65.00 H.T.
 
Reticulol Reticulol 1 mg Ref. BVT-0011-M001 Marque BIOVIOTICA 140.00 H.T.
 
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Antibiotic UK-1 Antibiotic UK-1 250 µg Ref. BVT-0013-C250 Marque BIOVIOTICA 70.00 H.T.
 
Antibiotic UK-1 Antibiotic UK-1 1 mg Ref. BVT-0013-M001 Marque BIOVIOTICA 210.00 H.T.
 
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Kojic acid Kojic acid 10 mg Ref. BVT-0019-M010 Marque BIOVIOTICA 45.00 H.T.
 
Rubiginone A2 Rubiginone A2 1 mg Ref. BVT-0023-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Rubiginone A2 Rubiginone A2 5 mg Ref. BVT-0023-M005 Marque BIOVIOTICA 440.00 H.T.
 
Rubiginone D2 Rubiginone D2 1 mg Ref. BVT-0024-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Rubiginone D2 Rubiginone D2 5 mg Ref. BVT-0024-M005 Marque BIOVIOTICA 440.00 H.T.
 
Mensacarcin Mensacarcin 1 mg Ref. BVT-0028-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Mensacarcin Mensacarcin 5 mg Ref. BVT-0028-M005 Marque BIOVIOTICA 360.00 H.T.
 
Aspyrone Aspyrone 1 mg Ref. BVT-0029-M001 Marque BIOVIOTICA 70.00 H.T.
 
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Aspyrone Aspyrone 5 mg Ref. BVT-0029-M005 Marque BIOVIOTICA 240.00 H.T.
 
Decoyinine Decoyinine 1 mg Ref. BVT-0030-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Oxyplicacetin Oxyplicacetin 1 mg Ref. BVT-0031-M001 Marque BIOVIOTICA 95.00 H.T.
 
Polyketomycin Polyketomycin 1 mg Ref. BVT-0033-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Aspinonene Aspinonene 1 mg Ref. BVT-0035-M001 Marque BIOVIOTICA 70.00 H.T.
 
Aspinonene Aspinonene 5 mg Ref. BVT-0035-M005 Marque BIOVIOTICA 210.00 H.T.
 
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