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The Source for Rare Active Natural Products

 
Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
 
 
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.

 

Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
 
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.
TargoSets™ - Screening Sets of characterized Natural Products
 
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
 
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
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Manumycin A Manumycin A 1 mg Ref. BVT-0091-M001 Marque BioViotica 100.00 € H.T.
 
Manumycin A Manumycin A 5 mg Ref. BVT-0091-M005 Marque BioViotica 405.00 € H.T.
 
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Chaetoglobosin A Chaetoglobosin A 1 mg Ref. BVT-0092-M001 Marque BioViotica 80.00 € H.T.
 
Chaetoglobosin A Chaetoglobosin A 5 mg Ref. BVT-0092-M005 Marque BioViotica 300.00 € H.T.
 
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Pyrrolcarbonyltaloside Pyrrolcarbonyltaloside 1 mg Ref. BVT-0095-M001 Marque BioViotica 85.00 € H.T.
 
Curvulin Curvulin 1 mg Ref. BVT-0097-M001 Marque BioViotica 140.00 € H.T.
 
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Borrelidin Borrelidin 500 µg Ref. BVT-0098-C500 Marque BioViotica 85.00 € H.T.
 
Borrelidin Borrelidin 1 mg Ref. BVT-0098-M001 Marque BioViotica 130.00 € H.T.
 
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Borrelidin Borrelidin 5 mg Ref. BVT-0098-M005 Marque BioViotica 430.00 € H.T.
 
Chrysomycin A Chrysomycin A 250 µg Ref. BVT-0099-C250 Marque BioViotica 150.00 € H.T.
 
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Chrysomycin A Chrysomycin A 1 mg Ref. BVT-0099-M001 Marque BioViotica 375.00 € H.T.
 
Chrysomycin B Chrysomycin B 250 µg Ref. BVT-0100-C250 Marque BioViotica 150.00 € H.T.
 
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Chrysomycin B Chrysomycin B 1 mg Ref. BVT-0100-M001 Marque BioViotica 365.00 € H.T.
 
Hormaomycin Hormaomycin 500 µg Ref. BVT-0107-C500 Marque BioViotica 270.00 € H.T.
 
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Hormaomycin Hormaomycin 1 mg Ref. BVT-0107-M001 Marque BioViotica 430.00 € H.T.
 
Deoxynojirimycin Deoxynojirimycin 1 mg Ref. BVT-0112-M001 Marque BioViotica 20.00 € H.T.
 
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Deoxynojirimycin Deoxynojirimycin 5 mg Ref. BVT-0112-M005 Marque BioViotica 75.00 € H.T.
 
N-Methyl-1-deoxynojirimycin N-Methyl-1-deoxynojirimycin 1 mg Ref. BVT-0130-M001 Marque BioViotica 100.00 € H.T.
 
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Rebeccamycin Rebeccamycin 250 µg Ref. BVT-0139-C250 Marque BioViotica 95.00 € H.T.
 
Rebeccamycin Rebeccamycin 1 mg Ref. BVT-0139-M001 Marque BioViotica 290.00 € H.T.
 
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Acetomycin Acetomycin 1 mg Ref. BVT-0150-M001 Marque BioViotica 100.00 € H.T.
 
Acetomycin Acetomycin 5 mg Ref. BVT-0150-M005 Marque BioViotica 340.00 € H.T.
 
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Tropodithietic acid Tropodithietic acid 1 mg Ref. BVT-0152-M001 Marque BioViotica 100.00 € H.T.
 
Tropodithietic acid Tropodithietic acid 5 mg Ref. BVT-0152-M005 Marque BioViotica 385.00 € H.T.
 
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Kirromycin Kirromycin 1 mg Ref. BVT-0157-M001 Marque BioViotica 195.00 € H.T.
 
Deoxymanumycin A Deoxymanumycin A 1 mg Ref. BVT-0158-M001 Marque BioViotica 140.00 € H.T.
 
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Chetomin Chetomin 1 mg Ref. BVT-0161-M001 Marque BioViotica 180.00 € H.T.
 
Chetomin Chetomin 5 mg Ref. BVT-0161-M005 Marque BioViotica 630.00 € H.T.
 
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Averantin Averantin 1 mg Ref. BVT-0169-M001 Marque BioViotica 85.00 € H.T.
 
Averantin Averantin 5 mg Ref. BVT-0169-M005 Marque BioViotica 340.00 € H.T.
 
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Sterigmatocystin Sterigmatocystin 1 mg Ref. BVT-0171-M001 Marque BioViotica 55.00 € H.T.
 
Sterigmatocystin Sterigmatocystin 5 mg Ref. BVT-0171-M005 Marque BioViotica 160.00 € H.T.
 
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Elaiophylin Elaiophylin 1 mg Ref. BVT-0185-M001 Marque BioViotica 100.00 € H.T.
 
Fumitremorgin C Fumitremorgin C 250 µg Ref. BVT-0189-C250 Marque BioViotica 90.00 € H.T.
 
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Fumitremorgin C Fumitremorgin C 1 mg Ref. BVT-0189-M001 Marque BioViotica 165.00 € H.T.
 
(+)-Brefeldin A (+)-Brefeldin A 1 mg Ref. BVT-0190-M001 Marque BioViotica 45.00 € H.T.
 
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Terrein Terrein 1 mg Ref. BVT-0193-M001 Marque BioViotica 120.00 € H.T.
 
Terrein Terrein 5 mg Ref. BVT-0193-M005 Marque BioViotica 375.00 € H.T.
 
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Terrein Terrein 10 mg Ref. BVT-0193-M010 Marque BioViotica 675.00 € H.T.
 
Geldanamycin Geldanamycin 100 µg Ref. BVT-0196-C100 Marque BioViotica 20.00 € H.T.
 
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Geldanamycin Geldanamycin 500 µg Ref. BVT-0196-C500 Marque BioViotica 35.00 € H.T.
 
Geldanamycin Geldanamycin 1 mg Ref. BVT-0196-M001 Marque BioViotica 60.00 € H.T.
 
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Geldanamycin Geldanamycin 5 mg Ref. BVT-0196-M005 Marque BioViotica 130.00 € H.T.
 
Elmycin B Elmycin B 1 mg Ref. BVT-0198-M001 Marque BioViotica 140.00 € H.T.
 
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Elmycin B Elmycin B 5 mg Ref. BVT-0198-M005 Marque BioViotica 415.00 € H.T.
 
Nargenicin A1 Nargenicin A1 1 mg Ref. BVT-0204-M001 Marque BioViotica 140.00 € H.T.
 
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Nargenicin A1 Nargenicin A1 5 mg Ref. BVT-0204-M005 Marque BioViotica 450.00 € H.T.
 
Thaxtomin A Thaxtomin A 1 mg Ref. BVT-0206-M001 Marque BioViotica 195.00 € H.T.
 
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Thaxtomin A Thaxtomin A 5 mg Ref. BVT-0206-M005 Marque BioViotica 675.00 € H.T.
 
Luisol A Luisol A 1 mg Ref. BVT-0212-M001 Marque BioViotica 150.00 € H.T.
 
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