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The Source for Rare Active Natural Products

 
Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
 
 
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.

 

Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
 
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.

TargoSets™ - Screening Sets of characterized Natural Products
 
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
 
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
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Isatropolone A Isatropolone A 1 mg Ref. BVT-0080-M001 Marque BIOVIOTICA 110.00 H.T.
 
Isatropolone A Isatropolone A 5 mg Ref. BVT-0080-M005 Marque BIOVIOTICA 330.00 H.T.
 
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Actinomycin D Actinomycin D 5 mg Ref. BVT-0089-M005 Marque BIOVIOTICA 40.00 H.T.
 
Actinomycin D Actinomycin D 25 mg Ref. BVT-0089-M025 Marque BIOVIOTICA 160.00 H.T.
 
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Actinomycin D Actinomycin D 100 mg Ref. BVT-0089-M100 Marque BIOVIOTICA 480.00 H.T.
 
Fumigaclavine A Fumigaclavine A 1 mg Ref. BVT-0090-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Fumigaclavine A Fumigaclavine A 5 mg Ref. BVT-0090-M005 Marque BIOVIOTICA 360.00 H.T.
 
Manumycin A Manumycin A 1 mg Ref. BVT-0091-M001 Marque BIOVIOTICA 85.00 H.T.
 
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Manumycin A Manumycin A 5 mg Ref. BVT-0091-M005 Marque BIOVIOTICA 310.00 H.T.
 
Chaetoglobosin A Chaetoglobosin A 1 mg Ref. BVT-0092-M001 Marque BIOVIOTICA 60.00 H.T.
 
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Chaetoglobosin A Chaetoglobosin A 5 mg Ref. BVT-0092-M005 Marque BIOVIOTICA 220.00 H.T.
 
Pyrrolcarbonyltaloside Pyrrolcarbonyltaloside 1 mg Ref. BVT-0095-M001 Marque BIOVIOTICA 70.00 H.T.
 
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Pyrrolcarbonyltaloside Pyrrolcarbonyltaloside 5 mg Ref. BVT-0095-M005 Marque BIOVIOTICA 280.00 H.T.
 
Curvulin Curvulin 1 mg Ref. BVT-0097-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Curvulin Curvulin 5 mg Ref. BVT-0097-M005 Marque BIOVIOTICA 360.00 H.T.
 
Borrelidin Borrelidin 500 µg Ref. BVT-0098-C500 Marque BIOVIOTICA 80.00 H.T.
 
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Borrelidin Borrelidin 1 mg Ref. BVT-0098-M001 Marque BIOVIOTICA 120.00 H.T.
 
Borrelidin Borrelidin 5 mg Ref. BVT-0098-M005 Marque BIOVIOTICA 390.00 H.T.
 
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Chrysomycin A Chrysomycin A 250 µg Ref. BVT-0099-C250 Marque BIOVIOTICA 130.00 H.T.
 
Chrysomycin A Chrysomycin A 1 mg Ref. BVT-0099-M001 Marque BIOVIOTICA 320.00 H.T.
 
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Chrysomycin B Chrysomycin B 250 µg Ref. BVT-0100-C250 Marque BIOVIOTICA 130.00 H.T.
 
Chrysomycin B Chrysomycin B 1 mg Ref. BVT-0100-M001 Marque BIOVIOTICA 320.00 H.T.
 
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Hormaomycin Hormaomycin 500 µg Ref. BVT-0107-C500 Marque BIOVIOTICA 260.00 H.T.
 
Hormaomycin Hormaomycin 1 mg Ref. BVT-0107-M001 Marque BIOVIOTICA 410.00 H.T.
 
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Deoxynojirimycin Deoxynojirimycin 1 mg Ref. BVT-0112-M001 Marque BIOVIOTICA 20.00 H.T.
 
Deoxynojirimycin Deoxynojirimycin 5 mg Ref. BVT-0112-M005 Marque BIOVIOTICA 70.00 H.T.
 
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N-Methyl-1-deoxynojirimycin N-Methyl-1-deoxynojirimycin 1 mg Ref. BVT-0130-M001 Marque BIOVIOTICA 85.00 H.T.
 
Rebeccamycin Rebeccamycin 250 µg Ref. BVT-0139-C250 Marque BIOVIOTICA 95.00 H.T.
 
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Rebeccamycin Rebeccamycin 1 mg Ref. BVT-0139-M001 Marque BIOVIOTICA 285.00 H.T.
 
Acetomycin Acetomycin 1 mg Ref. BVT-0150-M001 Marque BIOVIOTICA 90.00 H.T.
 
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Acetomycin Acetomycin 5 mg Ref. BVT-0150-M005 Marque BIOVIOTICA 270.00 H.T.
 
Tropodithietic acid Tropodithietic acid 1 mg Ref. BVT-0152-M001 Marque BIOVIOTICA 80.00 H.T.
 
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Tropodithietic acid Tropodithietic acid 5 mg Ref. BVT-0152-M005 Marque BIOVIOTICA 320.00 H.T.
 
Kirromycin Kirromycin 1 mg Ref. BVT-0157-M001 Marque BIOVIOTICA 160.00 H.T.
 
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Kirromycin Kirromycin 5 mg Ref. BVT-0157-M005 Marque BIOVIOTICA 495.00 H.T.
 
Deoxymanumycin A Deoxymanumycin A 1 mg Ref. BVT-0158-M001 Marque BIOVIOTICA 120.00 H.T.
 
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Deoxymanumycin A Deoxymanumycin A 5 mg Ref. BVT-0158-M005 Marque BIOVIOTICA 380.00 H.T.
 
Chetomin Chetomin 1 mg Ref. BVT-0161-M001 Marque BIOVIOTICA 140.00 H.T.
 
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Chetomin Chetomin 5 mg Ref. BVT-0161-M005 Marque BIOVIOTICA 490.00 H.T.
 
Averantin Averantin 1 mg Ref. BVT-0169-M001 Marque BIOVIOTICA 70.00 H.T.
 
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Averantin Averantin 5 mg Ref. BVT-0169-M005 Marque BIOVIOTICA 280.00 H.T.
 
Sterigmatocystin Sterigmatocystin 1 mg Ref. BVT-0171-M001 Marque BIOVIOTICA 30.00 H.T.
 
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Sterigmatocystin Sterigmatocystin 5 mg Ref. BVT-0171-M005 Marque BIOVIOTICA 105.00 H.T.
 
Elaiophylin Elaiophylin 1 mg Ref. BVT-0185-M001 Marque BIOVIOTICA 90.00 H.T.
 
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Elaiophylin Elaiophylin 5 mg Ref. BVT-0185-M005 Marque BIOVIOTICA 270.00 H.T.
 
Fumitremorgin C Fumitremorgin C 250 µg Ref. BVT-0189-C250 Marque BIOVIOTICA 65.00 H.T.
 
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Fumitremorgin C Fumitremorgin C 1 mg Ref. BVT-0189-M001 Marque BIOVIOTICA 110.00 H.T.
 
(+)-Brefeldin A (+)-Brefeldin A 1 mg Ref. BVT-0190-M001 Marque BIOVIOTICA 40.00 H.T.
 
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Terrein Terrein 1 mg Ref. BVT-0193-M001 Marque BIOVIOTICA 100.00 H.T.
 
Terrein Terrein 5 mg Ref. BVT-0193-M005 Marque BIOVIOTICA 320.00 H.T.
 
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