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The Source for Rare Active Natural Products

 
Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
 
 
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.

 

Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
 
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.

TargoSets™ - Screening Sets of characterized Natural Products
 
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
 
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
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Simocyclinone D8 Simocyclinone D8 5 mg Ref. BVT-0290-M005 Marque BIOVIOTICA 240.00 H.T.
 
Reductiomycin Reductiomycin 1 mg Ref. BVT-0292-M001 Marque BioViotica 150.00 H.T.
 
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Pimprinine Pimprinine 1 mg Ref. BVT-0297-M001 Marque BioViotica 140.00 H.T.
 
Pimprinine Pimprinine 5 mg Ref. BVT-0297-M005 Marque BioViotica 415.00 H.T.
 
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Aureothin Aureothin 1 mg Ref. BVT-0303-M001 Marque BioViotica 235.00 H.T.
 
Aureothin Aureothin 5 mg Ref. BVT-0303-M005 Marque BioViotica 740.00 H.T.
 
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Nebularine (high purity) Nebularine (high purity) 500 µg Ref. BVT-0304-C500 Marque BioViotica 95.00 H.T.
 
Nebularine (high purity) Nebularine (high purity) 1 mg Ref. BVT-0304-M001 Marque BioViotica 160.00 H.T.
 
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Sarcophine Sarcophine 2 mg Ref. BVT-0305-M002 Marque BioViotica 100.00 H.T.
 
Sarcophine Sarcophine 10 mg Ref. BVT-0305-M010 Marque BioViotica 425.00 H.T.
 
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(+)-Aphidicolin (+)-Aphidicolin 1 mg Ref. BVT-0307-M001 Marque BioViotica 70.00 H.T.
 
(+)-Aphidicolin (+)-Aphidicolin 5 mg Ref. BVT-0307-M005 Marque BioViotica 255.00 H.T.
 
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(+)-Aphidicolin (+)-Aphidicolin 25 mg Ref. BVT-0307-M025 Marque BioViotica 900.00 H.T.
 
Papyracillic acid A Papyracillic acid A 500 µg Ref. BVT-0308-C500 Marque BioViotica 150.00 H.T.
 
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Papyracillic acid A Papyracillic acid A 1 mg Ref. BVT-0308-M001 Marque BioViotica 235.00 H.T.
 
(S)-(+)-Ascochin (S)-(+)-Ascochin 1 mg Ref. BVT-0309-M001 Marque BioViotica 135.00 H.T.
 
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(S)-(+)-Ascochin (S)-(+)-Ascochin 5 mg Ref. BVT-0309-M005 Marque BioViotica 400.00 H.T.
 
Pseudoanguillosporin A Pseudoanguillosporin A 500 µg Ref. BVT-0311-C500 Marque BioViotica 140.00 H.T.
 
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Pseudoanguillosporin A Pseudoanguillosporin A 1 mg Ref. BVT-0311-M001 Marque BioViotica 235.00 H.T.
 
Strobilurin B Strobilurin B 500 µg Ref. BVT-0312-C500 Marque BioViotica 130.00 H.T.
 
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Strobilurin B Strobilurin B 1 mg Ref. BVT-0312-M001 Marque BioViotica 205.00 H.T.
 
5-Hydroxy-2-methyl-4-chromanone 5-Hydroxy-2-methyl-4-chromanone 500 µg Ref. BVT-0322-C500 Marque BioViotica 135.00 H.T.
 
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5-Hydroxy-2-methyl-4-chromanone 5-Hydroxy-2-methyl-4-chromanone 1 mg Ref. BVT-0322-M001 Marque BioViotica 235.00 H.T.
 
Alternariol monomethyl ether Alternariol monomethyl ether 500 µg Ref. BVT-0323-C500 Marque BioViotica 85.00 H.T.
 
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Alternariol monomethyl ether Alternariol monomethyl ether 1 mg Ref. BVT-0323-M001 Marque BioViotica 130.00 H.T.
 
Antibiotic L-696,474 Antibiotic L-696,474 500 µg Ref. BVT-0331-C500 Marque BioViotica 140.00 H.T.
 
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Aphidicolin 17-acetate Aphidicolin 17-acetate 250 µg Ref. BVT-0337-C250 Marque BioViotica 95.00 H.T.
 
Antibiotic PF 1052 Antibiotic PF 1052 500 µg Ref. BVT-0338-C500 Marque BioViotica 120.00 H.T.
 
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Antibiotic PF 1052 Antibiotic PF 1052 1 mg Ref. BVT-0338-M001 Marque BioViotica 205.00 H.T.
 
Ascolactone Ascolactone 500 µg Ref. BVT-0340-C500 Marque BioViotica 100.00 H.T.
 
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Ascolactone Ascolactone 1 mg Ref. BVT-0340-M001 Marque BioViotica 175.00 H.T.
 
Elasnin Elasnin 1 mg Ref. BVT-0342-M001 Marque BioViotica 140.00 H.T.
 
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Elasnin Elasnin 5 mg Ref. BVT-0342-M005 Marque BioViotica 415.00 H.T.
 
Aureothricin Aureothricin 500 µg Ref. BVT-0345-C500 Marque BioViotica 45.00 H.T.
 
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Aureothricin Aureothricin 1 mg Ref. BVT-0345-M001 Marque BioViotica 95.00 H.T.
 
Viomellein Viomellein 500 µg Ref. BVT-0359-C500 Marque BioViotica 140.00 H.T.
 
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Viomellein Viomellein 1 mg Ref. BVT-0359-M001 Marque BioViotica 235.00 H.T.
 
(R)-Semivioxanthin (R)-Semivioxanthin 500 µg Ref. BVT-0360-C500 Marque BioViotica 135.00 H.T.
 
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(R)-Semivioxanthin (R)-Semivioxanthin 1 mg Ref. BVT-0360-M001 Marque BioViotica 225.00 H.T.
 
Aranciamycin Aranciamycin 500 µg Ref. BVT-0364-C500 Marque BioViotica 140.00 H.T.
 
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Aranciamycin Aranciamycin 1 mg Ref. BVT-0364-M001 Marque BioViotica 235.00 H.T.
 
Xanthomegnin Xanthomegnin 500 µg Ref. BVT-0365-C500 Marque BioViotica 140.00 H.T.
 
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Xanthomegnin Xanthomegnin 1 mg Ref. BVT-0365-M001 Marque BioViotica 235.00 H.T.
 
(R)-Semixanthomegnin (R)-Semixanthomegnin 500 µg Ref. BVT-0366-C500 Marque BioViotica 135.00 H.T.
 
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(R)-Semixanthomegnin (R)-Semixanthomegnin 1 mg Ref. BVT-0366-M001 Marque BioViotica 225.00 H.T.
 
Actinomycin X2 Actinomycin X2 1 mg Ref. BVT-0375-M001 Marque BioViotica 95.00 H.T.
 
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Actinomycin X2 Actinomycin X2 5 mg Ref. BVT-0375-M005 Marque BioViotica 290.00 H.T.
 
Diastovaricin I Diastovaricin I 500 µg Ref. BVT-0381-C500 Marque BioViotica 100.00 H.T.
 
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Diastovaricin I Diastovaricin I 1 mg Ref. BVT-0381-M001 Marque BioViotica 160.00 H.T.
 
Saquayamycin B1 Saquayamycin B1 500 µg Ref. BVT-0382-C500 Marque BioViotica 100.00 H.T.
 
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