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The Source for Rare Active Natural Products

 
Bioviotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.
 
 
BioViotica focuses especially on the discovery and fermentation (small-scale production in the range of grams) of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. Based on 30 years of know-how in the field of natural products, BioViotica also offers services, including: a) Structure determination of natural products from raw material. b) Optimization of microbial strains. c) Custom strain cultivations.

 

Featured Items
Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.
 
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.
Mycotoxin. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.
TargoSets™ - Screening Sets of characterized Natural Products
 
The birch tree has been known for a long time for its healing properties in folk medicine. It can be expected that Betulin an active principle of the birch tree could be used for the treatment of various pathologies. Since, Betulin has three active positions in its structure, secondary hydroxyl group at C-3, primary hydroxyl group at C-28 and a double C-C bonding at C-20, chemical modulations can be performed in order to obtain different types of derivatives. Betulin can be rapidly converted to its „more“ active derivatives, with a wide spectrum of biological and pharmacological activities such as: anti-inflammatory, antimalarial, anti-HIV and antineoplasic.
 
The Mycotoxin TargoSet™ offers a panel of well-characterized and highly pure compounds for screening experiments, cell-based research or as standard compounds. Mycotoxins are secondary metabolites produced by microfungi. Because of their wide spectrum of biological and pharmacological activities, some are used in research as antibiotics, cell growth promotants or cytotoxic compounds in cancer cells. Mycotoxins are harmful to animal and human health if they enter the food chain via contaminated crops and fruits or through processed food and feed products.
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Cytochalasin J Cytochalasin J 1 mg Ref. BVT-0450-M001 Marque BioViotica 100.00 € H.T.
 
3-Deoxyaphidicolin 3-Deoxyaphidicolin 250 µg Ref. BVT-0451-C250 Marque BioViotica 75.00 € H.T.
 
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3-Deoxyaphidicolin 3-Deoxyaphidicolin 1 mg Ref. BVT-0451-M001 Marque BioViotica 225.00 € H.T.
 
Aphidicolin-3alpha,18-acetonide Aphidicolin-3alpha,18-acetonide 250 µg Ref. BVT-0452-C250 Marque BioViotica 80.00 € H.T.
 
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Aphidicolin-3alpha,18-acetonide Aphidicolin-3alpha,18-acetonide 1 mg Ref. BVT-0452-M001 Marque BioViotica 240.00 € H.T.
 
Phomoxanthone A Phomoxanthone A 5 mg Ref. BVT-0453-M005 Marque BioViotica 340.00 € H.T.
 
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Venturicidin A Venturicidin A 1 mg Ref. BVT-0454-M001 Marque BioViotica 130.00 € H.T.
 
Pyridomycin Pyridomycin 1 mg Ref. BVT-0455-M001 Marque BioViotica 290.00 € H.T.
 
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Telithromycin Telithromycin 1 mg Ref. BVT-0456-M001 Marque BioViotica 45.00 € H.T.
 
Telithromycin Telithromycin 10 mg Ref. BVT-0456-M010 Marque BioViotica 130.00 € H.T.
 
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Luteoreticulin Luteoreticulin 500 µg Ref. BVT-0457-C500 Marque BioViotica 150.00 € H.T.
 
Luteoreticulin Luteoreticulin 1 mg Ref. BVT-0457-M001 Marque BioViotica 270.00 € H.T.
 
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Cochliodone A Cochliodone A 1 mg Ref. BVT-0458-M001 Marque BioViotica 160.00 € H.T.
 
Chaetoglobosin C Chaetoglobosin C 1 mg Ref. BVT-0460-M001 Marque BioViotica 235.00 € H.T.
 
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Chaetoglobosin F Chaetoglobosin F 1 mg Ref. BVT-0461-M001 Marque BioViotica 195.00 € H.T.
 
Lysolipin I Lysolipin I 5 mg Ref. BVT-0037-M005 Marque BioViotica 545.00 € H.T.
 
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17-AAG 17-AAG 5 mg Ref. BVT-0244-M005 Marque BioViotica 80.00 € H.T.
 
Alternariol monomethyl ether Alternariol monomethyl ether 5 mg Ref. BVT-0323-M005 Marque BioViotica 480.00 € H.T.
 
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Alternariol monomethyl ether Alternariol monomethyl ether 10 mg Ref. BVT-0323-M010 Marque BIOVIOTICA 630.00 € H.T.
 
Culpin Culpin 1 mg Ref. BVT-0462-M001 Marque BioViotica 100.00 € H.T.
 
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Culpin Culpin 5 mg Ref. BVT-0462-M005 Marque BioViotica 305.00 € H.T.
 
Culpin Culpin 10 mg Ref. BVT-0462-M010 Marque BioViotica 460.00 € H.T.
 
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Lupallene B Lupallene B 1 mg Ref. BVT-0466-M001 Marque BioViotica 125.00 € H.T.
 
Lupallene B Lupallene B 5 mg Ref. BVT-0466-M005 Marque BioViotica 370.00 € H.T.
 
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Lupallene D Lupallene D 1 mg Ref. BVT-0467-M001 Marque BioViotica 125.00 € H.T.
 
Lupallene D Lupallene D 5 mg Ref. BVT-0467-M005 Marque BioViotica 370.00 € H.T.
 
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Dimethylsulfoniopropionate (DMSP) . hydrochloride Dimethylsulfoniopropionate (DMSP) . hydrochloride 100 mg Ref. BVT-0468-M100 Marque BioViotica 130.00 € H.T.
 
Fridamycin A Fridamycin A 1 mg Ref. BVT-0469-M001 Marque BioViotica 95.00 € H.T.
 
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Fridamycin B Fridamycin B 1 mg Ref. BVT-0470-M001 Marque BioViotica 95.00 € H.T.
 
Fridamycin E Fridamycin E 1 mg Ref. BVT-0472-M001 Marque BioViotica 95.00 € H.T.
 
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Violacein Violacein 1 mg Ref. BVT-0473-M001 Marque BioViotica 415.00 € H.T.
 
Bafilomycin D (high purity) Bafilomycin D (high purity) 1 mg Ref. BVT-0475-M001 Marque BioViotica 195.00 € H.T.
 
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(+)-Rubiginone B2 (+)-Rubiginone B2 1mg Ref. BVT-0026-M01 Marque BIOVIOTICA 125.00 € H.T.
 
Alternariol Alternariol 1 mg Ref. BVT-0465-M001 Marque BioViotica 75.00 € H.T.
 
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Alternariol Alternariol 5 mg Ref. BVT-0465-M005 Marque BioViotica 245.00 € H.T.
 
Rubiginone B2 Rubiginone B2 1 mg Ref. BVT-0026-M001 Marque BioViotica 145.00 € H.T.
 
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Terreic acid Terreic acid 1 mg Ref. BVT-0477-M001 Marque BioViotica 60.00 € H.T.
 
Terreic acid Terreic acid 5 mg Ref. BVT-0477-M005 Marque BioViotica 195.00 € H.T.
 
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Helvolic acid Helvolic acid 5 mg Ref. BVT-0435-M005 Marque BioViotica 225.00 € H.T.
 
Decoyinine Decoyinine 5 mg Ref. BVT-0030-M005 Marque BioViotica 300.00 € H.T.
 
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Concanamycin A (high purity) Concanamycin A (high purity) 5 mg Ref. BVT-0237-M005 Marque BioViotica 1340.00 € H.T.
 
Concanamycin B (high purity) Concanamycin B (high purity) 1 mg Ref. BVT-0253-M001 Marque BioViotica 730.00 € H.T.
 
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Concanamycin C (high purity) Concanamycin C (high purity) 1 mg Ref. BVT-0254-M001 Marque BioViotica 730.00 € H.T.
 
Collinolactone Collinolactone 250 µg Ref. BVT-0480-C250 Marque BioViotica 170.00 € H.T.
 
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Collinolactone Collinolactone 1 mg Ref. BVT-0480-M001 Marque BioViotica 515.00 € H.T.
 
Rubiginone A2 Rubiginone A2 5 mg Ref. BVT-0023-M005 Marque Bioviotica 600.00 € H.T.
 
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Rubiginone D2 Rubiginone D2 5 mg Ref. BVT-0024-M005 Marque Bioviotica 600.00 € H.T.
 
Palmarumycin C3-5,8-quinone Palmarumycin C3-5,8-quinone 5 mg Ref. BVT-0066-M005 Marque Bioviotica 480.00 € H.T.
 
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Mutolide Mutolide 5 mg Ref. BVT-0070-M005 Marque Bioviotica 480.00 € H.T.
 
Isatropolone A Isatropolone A 5 mg Ref. BVT-0080-M005 Marque Bioviotica 385.00 € H.T.
 
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